Cerebral expression of metabotropic glutamate recptors is modified by deep brain stimulation (DBS) of the subthalamic nucleus (STN) in a rat model of Parkinson’s disease

Katharina Faust, Peter Vajkoczy, Andreas Kupsch & Daniel Harnack
Objective: Modulation of metabotropic glutamate receptors (mGluRs) has evolved a therapeutic target for Parkinson’s disease (PD), both in alleviating PD symptoms and in slowing disease progression. MGluRs modulate synaptic transmission throughout the basal ganglia, and it is assumed that nigral[for full text, please go to the a.m. URL]