The role of RTK inhibitor targeting axl in glioma cell lines

Julia Sophie Onken, Irina Kremenetskaia, Melina Nieminen-Kelhä, Robert Torka, Axel Ullrich & Peter Vajkoczy
Objective: As previously reported the role of Receptor tyrosine kinase (RTK) in brain tumor growth become more important. Axl has been revealed as an important RTK, which mediates tumor growth and proliferation. Axl/gas6 overexpression has been found in a multitude of human cancers including glioblastoma,[for full text, please go to the a.m. URL]