Multicolor labeling of EGFR-amplified glioblastoma cells allows for tracking of individual cell clones in vitro and in vivo

Katrin Liffers, Kristoffer Riecken, Boris Fehse, Manfred Westphal, Katrin Lamszus & Alexander Schulte
Objective: The current study aimed at analyzing the molecular requirements for tumor initiation of EGFR-amplified, EGFRvIII-positive glioblastoma (GBM) cells in vitro and in vivo. Method: GBM-derived EGFR-amplified, EGFRvIII-positive BS153 cells were analyzed for their tumor-initiating capacity in[for full text, please go to the a.m. URL]