Effect of the sphingosine-1-phosphate receptor modulator FTY720 on the outcome in a mouse model of focal cortical cryolesion

Nelli Hennig, Christiane Albert-Weissenberger, Christoph Kleinschnitz & Anna-Leena Sirén
Objective: Traumatic brain injury (TBI), a leading cause of death and disability, characteristically results in acute inflammation and massive brain edema. The molecular mechanisms of edema formation after TBI have not been fully elucidated and the contribution of the acute inflammatory response to [for full text, please go to the a.m. URL]