The treatment of microglia with p38MAPK blockers leads to decreased matrix metalloprotease (MMP) 9 expression and prolonged survival in glioma-bearing mice

Darko S. Marković, Ku Min-Chi, Helmut Kettenmann & Jürgen C. W. Kiwit
Objective: Introduction:The recurrence of malignant glioma is one of the major obstacles in glioma therapy and the reason for poor survival of the patients. Glioma cells infiltrate healthy brain and become inaccessible to surgical resection. Microglia supports glioma infiltration of the brain by increased[for full text, please go to the a.m. URL]