Inhibition of Fatty acid synthase (FAS) induces apoptosis in a human gliomblastoma cell culture

Susanne Grube, Pedro Dünisch, Maren Klausnitzer, Rolf Kalff & Christian Ewald
Objective: High level of fatty acid synthase (FAS) expression have been reported in different tumors, including prostate, breast and ovarian cancer, and its inhibition reduces tumor growth in vitro and in vivo via apoptotic pathways. We showed increased FAS expression level in glioblastoma compared [for full text, please go to the a.m. URL]