No impact of sedatives on critical glucose metabolism in brain-injured patients: a microdialysis study

Daniel N. Hertle, Edgar Santos, Anna M. Hagenston, Christine Dictus, Daniel Haux, Andreas W. Unterberg & Oliver W. Sakowitz
Objective: Sufficient glycolysis and cellular respiration are vital components for survival of neuronal tissue after brain injury. Critical glucose concentrations below 0.2 mmol/l lead to coma and neuronal death. Reduction of brain energy consumption is therefore a promising target for prevention[for full text, please go to the a.m. URL]