Comprehensive high-resolution genomic profiling and cytogenetics of two pediatric and one adult medulloblastoma

Li-Xin Xu, Heidrun Holland, Peter Ahnert, Manfred Bauer, Jürgen Meixensberger & Wolfgang Krupp
Objective: Medulloblastoma (WHO grade IV) is a malignant, invasive embryonal tumor which mainly occurs in children and represents less than 1% of all adult brain tumors. Current clinical management includes the combination of surgical resection, craniospinal radiotherapy and chemotherapy. Furthermore,[for full text, please go to the a.m. URL]