Distinct Aspergillus fumigatus morphotypes induce neutrophilic CXCR4high myeloid-derived suppressor cells through a Dectin-1-mediated mechanism

N. Rieber, M. Bouzani, M. Ost, L. Hofer, I. Schäfer, M. Mezger, M. Pfeiffer, H. Einsele, R. Handgretinger, J. Löffler & D. Hartl
Introduction: The coordinated action of both innate and adaptive immunity is essential to protect the host against Aspergillus fumigatus. Innate myeloid cells recognize the fungus, while T cells orchestrate long-term immune responses. However, overreactive T cell responses drive hyperinflammation with[for full text, please go to the a.m. URL]