Anti-Interleukin-6 (IL-6) and Anti-TNF-alpha treatments do not have a negative impact on the Cytomegalovirus- (CMV) specific Interferon-gamma immune response in children with Juvenile Idiopathic Arthritis (JIA) in vitro

R. Trippen, G. Almanzar, K. Sustal, K. Höfner & M. Prelog
Background: Previous studies showed lower proportions of CD28+ T-cells in Cytomegalovirus (CMV)-seropositive healthy donors (HD), which could not be shown in patients with Juvenile Idiopathic Arthritis (JIA), a T-cell-mediated autoimmune disease in children and adolescents. However, data on CMV-specific[for full text, please go to the a.m. URL]