Specific identification of small genomic structural variations using next generation sequencing data

Matthias Kuhn & Ingo Röder
Introduction: Next generation sequencing (NGS) is a technique that promises to unbundle genetic variability with low bias and hence to advance our understanding of, e.g. tumorigenesis. Changes of single nucleotides (SNV) and insertions/ deletions of up to 50 nucleotides (Indels) form the best known[for full text, please go to the a.m. URL]