Tumor-derived factors convert mesenchymal stromal cells (MSC) from healthy buccal mucosa to the activated phenotype of carcinoma-associated MSC

Philip Alexander Dißmann, Benjamin Kansy, Stephan Lang & Sven Brandau
Introduction: Mesenchymal Stromal Cells (MSC) are multipotent, fibroblast-like progenitor cells. Their role in inflammatory tissue and tumor environment has been of highest interest in the past years. Yet, very little is known about MSC from tumor tissue (tMSC) and modulation of MSC by tumor-derived[for full text, please go to the a.m. URL]