The SDF-1-CXCR4-axis – tracking cell traffic in the cancer stem cell niche of head and neck squamous cell carcinoma

Anne Faber, Ulrich R. Gößler, Karl Hörmann, Johannes D. Schultz & Jens Stern-Sträter
Introduction: Antineoplastic treatments can eradicate a majority of proliferating malignant cells within tumors. However, there is increasing evidence that there is a subpopulation of resistant cells that cannot be reached by these regimens. These cancer stem cells (CSCs) have features of somatic stem[for full text, please go to the a.m. URL]