Methods in Genetics in inherited retinal disorders and Gene therapy trials

Christina Zeitz, S. El Shamieh, I. Audo & J.-A. Sahel
Inherited retinal disorders (IRD) are clinically and genetically heterogeneous with more than 150 gene defects accounting for the diversity of disease phenotypes. Over the past two decades, three main approaches including Sanger sequencing, arrayed primer extension (APEX) chip technology and homozygosity[for full text, please go to the a.m. URL]