Label-free multiphoton microscopy extends the neuropathological armamentarium: Visualization of hippocampal sclerosis

Ortrud Uckermann, Roberta Galli, Roland Coras, Matthias Meinhardt, Ingmar Blümcke, Gerald Steiner & Matthias Kirsch
Question: Multiphoton microscopy can be applied to fresh tissue and visualizes morphochemical properties and structure without the need for labeling or tissue preparation. Coherent anti-Stokes Raman scattering (CARS) addresses the lipid content, second harmonic generation (SHG) shows collagen, and two-photon[for full text, please go to the a.m. URL]
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