Absence of sensory neurotransmitters substance P and α-calcitonin gene-related peptide impact on osteoblast and osteoclast metabolism

Tanja Niedermair, Stephan Schirner, Joachim Grifka & Susanne Grässel
Objectives: In previous studies we observed reduced biomechanical bone strength and matrix integrity in mice lacking the sensory neurotransmitter substance P (SP) [ref:1]. A similar effect on bone microarchitecture has been described for α-calcitonin gene-related peptide (α-CGRP)-deficient[for full text, please go to the a.m. URL]
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