Frequency of occurrence of recessive 35delG mutation in GJB2 gene in children with sensorineural hearing loss

Anastasiya Levaya-Smaliak, Elena Merculova & Nina Danilenko
Introduction: A human being is known to have about 100 genes associated with deafness and hearing loss, which are located in both the nucleus and mitochondria. Most commonly detected mutations are those in the GJB2 gene, mononucleotic deletion 35 delG including, which accounts for up to 50% of cases of neurosensory hearing loss in Europeans. We studied frequency of occurrence of the above-mentioned mutation among Belarusian schoolchildren with the impaired hearing. Methods: 35delG mutation was...