Detection of the intercellular adhesion gene cluster (ica) in clinical Staphylococcus aureus isolates

Amirmorteza Ebrahimzadeh Namvar, Babak Asghari, Fatemeh Ezzatifar, Gholamreza Azizi & Abdolaziz Rastegar Lari
Staphylococcus aureus is a major hospital and community pathogen having the aptitude to cause a wide variety of infections in men. The ability of microorganisms to produce biofilm facilitates them to withstand the host immune response and is recognized as one factor contributing to chronic or persistent infections. It was demonstrated that the ica-encoded genes lead to the biosynthesis of polysaccharide intercellular adhesion (PIA) molecules, and may be involved in the accumulation phase of biofilm...