Prognostic factors of resected node-positive lung cancer: location, extent of nodal metastases, and multimodal treatment

Alessandro Marra, Gunther Richardsen, Wolfgang Wagner, Carsten Müller-Tidow, Olaf M. Koch & Ludger Hillejan
Objective: To investigate the prognostic significance of location and extent of lymph node metastasis in resected non-small cell lung cancer (NSCLC), and to weigh up the influence of treatment modalities on survival. Patients and method: On exploratory analysis, patients were grouped according to location and time of diagnosis of nodal metastasis: group I, pN2-disease in the aortopulmonary region (N=14); group II, pN2-disease at other level (N=30); group III, cN2-disease with response to induction treatment (ypN0;...