This dataset includes hourly output from the WRF-Chem simulation model for North America at resolution of 27 km for June 29, 2016 through July 31, 2019. WRF-Chem is the Weather Research and Forecasting (WRF) model coupled with Chemistry. The output provides baseline conditions for comparison to data from ACT-America airborne campaigns conducted to study atmospheric CO2 and CH4 in 2016 to 2019. The WRF-Chem (ver. 3.6.1) model was driven by meteorological conditions and sea-surface temperatures....