New experimental support for long standing concepts of polygenic genetics implies that the Mendelian genetic paradigm needs to be revised

Diethard Tautz, Richard Reeves & Luisa F Pallares
The field of Genetics started flourishing after the rediscovery of the Mendelian laws of inheritance at the beginning of the 20th century. These laws are based on a discrete classification of phenotypes and their causative genes. Such a Mendelian way of thinking forms the foundation of modern molecular biology, with its experimental paradigm that a gene function is inferred from the knock-out of the gene. However, most phenotypes are not discrete. Human height, for example,...
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