Hyperemic stress myocardial perfusion cardiovascular magnetic resonance in mice at 3 Tesla: initial experience and validation against microspheres

Roy Jogiya, Marcus Makowski, Alkystsis Phinikaridou, Ashish S. Patel, Christian Jansen, Niloufar Zarinabad, Amedeo Chiribiri, René Botnar, Eike Nagel, Sebastian Kozerke & Sven Plein
Background Dynamic first pass contrast-enhanced myocardial perfusion is the standard CMR method for the estimation of myocardial blood flow (MBF) and MBF reserve in man, but it is challenging in rodents because of the high temporal and spatial resolution requirements. Hyperemic first pass myocardial perfusion CMR during vasodilator stress in mice has not been reported. Methods Five C57BL/6 J mice were scanned on a clinical 3.0 Tesla Achieva system (Philips Healthcare, Netherlands). Vasodilator stress was...
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