Resilience of bacterial quorum sensing against fluid flow

Philippe Emge, Jens Moeller, Hongchul Jang, Roberto Rusconi, Yutaka Yawata, Roman Stocker & Viola Vogel
Quorum sensing (QS) is a population-density dependent chemical process that enables bacteria to communicate based on the production, secretion and sensing of small inducer molecules. While recombinant constructs have been widely used to decipher the molecular details of QS, how those findings translate to natural QS systems has remained an open question. Here, we compare the activation of natural and synthetic Pseudomonas aeruginosa LasI/R QS systems in bacteria exposed to quiescent conditions and controlled flows....
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