Two interacting axis proteins contribute to meiotic stability in autotetraploid Arabidopsis arenosa

Polyploidy, which results from whole genome duplication (WGD), has shaped the evolution of eukaryotic genomes in all kingdoms. In the shorter term, polyploidy is also implicated in adaptation, domestication and speciation. Yet when WGD newly occurs, the resulting neopolyploids face numerous challenges. A particularly pernicious problem is the segregation of multiple chromosome copies in meiosis. Evolution can overcome this challenge, likely through modification of chromosome pairing and recombination to prevent deleterious multivalent chromosome associations, but...
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