Dendritic cells and antiviral defenses

Marc Dalod
The goal of our research is to identify new molecular pathways regulating the biology of DC subsets or more generally innate immune responses to viral infection. The model used is murine cytomegalovirus (MCMV) infection. The specific aims are 1) to determine the molecular bases regulating in vivo differentiation and anti-viral functions of DC subsets, 2) to investigate further NK cell anti-viral and immunoregulatory functions during viral infection, and 3) to identify viral molecules and cellular...