Response of Caenorhabditis elegans to infection by Drechmeria coniospora at 12 hours post exposure

Jonathan Ewbank
Transcription profiling of Caenorhabditis elegans after an exposure of 4 hours to the fungal pathogen Drechmeria coniospora, and a post exposure of 12 hours. This experiment has been deposited in the Array Express database under reference number E-MEXP-767.

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Response of Caenorhabditis elegans to infection by Drechmeria coniospora

Jonathan Ewbank
Caenorhabditis elegans is a widely used invertebrate model organism. We are using C. elegans to dissect the molecular basis of host-pathogen interactions. We are investigating host innate immune defences. There is mounting evidence that resistance to infection in the nematode involves both a dedicated antimicrobial response and a more general reaction to infection-associated cellular stress. Our studies indicate that multiple signal pathways cooperate to control the expression of antimicrobial peptides and proteins. We are starting...

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  • 2010
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  • 2010
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