Synthesis of Unsymmetrically Substituted 4,6,10-Trihydroxy-1,4,6,10-tetra­azaadamantanes via Intramolecular Cyclization of Tris(β-oximinoalkyl)amines

Artem N. Semakin, Alexey Yu. Sukhorukov, Yulia V. Nelyubina, Sema L. Ioffe & Vladimir A. Tartakovsky
The cyclotrimerization of oximino groups in unsymmetrically substituted tris(β-oximinoalkyl)amines was studied. A general approach to the synthesis of 4,6,10-trihydroxy-1,4,6,10-tetraazaadamantanes containing different substituents at bridgehead carbon atoms was developed from available aliphatic nitro compounds.