Simulation and Visualization of Medical Application to the Inner Ear of the Guinea Pig to Reduce Animal Experiments

Martin Hering-Bertram, Norbert Siedow, Oliver Tse, Stefan K. Plontke & Ruth Gill
We present a novel approach to simulate drug application to the inner ear of the guinea pig with the goal to reduce animal experiments and to increase the accuracy of measurements. The framework is based on a tetrahedral grid representing the individual compartments of the cochlea, associated with a finite element model used to simulate medical diffusion and clearance. In a first simulation scenario, we were able to compute transfer coefficients between the inner compartments...