Synthesis and Biological Activities of a Novel Naringin based Heterocyclic Derivatives

Shehdeh Jodeh, Nuha Shawarb, Nidal Jaradat, Ismail Warad, Fatima Hussein, Moutasim El-Masri & Rachid Salghi
A number of naringin based heterocyclic derivatives dioxolane and imidazolidine have been synthesized and evaluated for their antioxidant and biological activities. The chemical structures of the newly synthesized compounds were verified on the basis of spectral and elemental methods of analysis. Investigation of antibacterial activity of these compounds was determined by measuring MIC value using broth micro dilution method for Gram-positive and Gram-negative bacteria, among the various synthesized compounds. Dioxolane showed the highest antibacterial activity...
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