Novel nanoparticle drug delivery systems: application in the in vitro study of Bisnaphthalimidopropyl derivatives against human colorectal cancer cell lines

Mathieu Brunet
Colorectal cancer is one of the most severe causes of mortality worldwide accounting for 10% of total cancer cases. Although recent advances in early diagnosis have reduced the mortality rate associated with CRC, patients suffering from the later metastatic stage of the disease have a 5-year survival rate of only 14%. To enhance the current treatment options, bisnaphthalimides (BNIPs) were developed as a new group of chemotherapeutic agents. Presenting promising results in vitro against colon...
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