The endoplasmic reticulum chaperone BiP is a closure-accelerating co-chaperone of Grp94

Ming Sun
Structural and functional analysis of Hsp70 and Hsp90 chaperones has advanced significantly over the last decade. However, within the cell Hsp70 and Hsp90 often work together, and little is known about the molecular mechanisms that allow these two chaperones to productively coordinate their activities. Much of my thesis is focused on discoveries that reveal a high level of regulation in how Hsp70 and Hsp90 work together. I specifically focus on the endoplasmic reticulum (ER)-specific Hsp70/Hsp90...
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