Data from: Rat aversion to isoflurane versus carbon dioxide

Devina Wong, I. Joanna Makowska, Weary M. Weary, I. J. Makowska, D. M. Weary & D. Wong
Some experts suggest that sedation of laboratory rodents with isoflurane before euthanasia with carbon dioxide (CO2) is a humane alternative to euthanasia with CO2 alone, but little research has compared aversion to these agents. Albino rats were tested in a light/dark box where they had the choice between remaining in a dark compartment filling with isoflurane or CO2, or escaping to a lit compartment. Experiment 1 validated the procedure by confirming that rats responded to...
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