Data from: Manipulation of the N-terminal sequence of the Borna disease virus X protein improves its mitochondrial targeting and neuroprotective potential

Cécile A. Ferré, Noélie Davezac, Anne Thouard, Jean-Michel Peyrin, Pascale Belenguer, Marie-Christine Miquel, Daniel Gonzalez-Dunia & Marion Szelechowski
To favor their replication, viruses express proteins that target diverse mammalian cellular pathways. Due to the limited size of many viral genomes, such proteins are endowed with multiple functions, which require targeting to different subcellular compartments. One salient example is the X protein of Borna disease virus, which is expressed both at the mitochondria and in the nucleus. Moreover, we recently demonstrated that mitochondrial X protein is neuroprotective. In this study, we sought to examine...
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