Data from: Comparative analysis of 2D and 3D distance measurements to study spatial genome organization

Elizabeth H. Finn, Gianluca Pegoraro, Sigal Shachar & Tom Misteli
The spatial organization of genomes is non-random, cell-type specific, and has been linked to cellular function. The investigation of spatial organization has traditionally relied extensively on fluorescence microscopy. The validity of the imaging methods used to probe spatial genome organization often depends on the accuracy and precision of distance measurements. Imaging-based measurements may either use 2 dimensional datasets or 3D datasets which include the z-axis information in image stacks. Here we compare the suitability of...
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