Adjusting ORG counts for low coverage genomes, or omitting low coverage species, improves correlation between RelCP and functional ORG number.

Deborah Bird, William Murphy, Lester Fox-Rosales, Iman Hamid, Robert Eagle & Blaire Van Valkenburgh
(a), Plot from figure 2b; RelCP vs. functional ORGs (log10). Blue circles: species with low coverage (≤ 6x) genome assemblies (r2 = 0.76, P < 0.0001). (b), Adjusted regression plot. Number of functional ORGs in low-coverage genomes is increased by 39.7%. Percent increase is derived by comparing the number of ORGs extracted from earlier, low-coverage draft genomes to the number from current ≥ 6x coverage assemblies, averaged over four available relevant cases (elephant, dog, cat,...
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