Data from: Gene signature of the human pancreatic ε-cell

Giselle Dominguez Gutierrez, Jinrang Kim, Ann-Hwee Lee, Jenny Tong, JingJing Niu, Sarah Gray, Yi Wei, Yueming Ding, Min Ni, Christina Adler, Andrew J. Murphy, Jesper Gromada, Yurong Xin & Sarah M Gray
The ghrelin producing ε-cell represents the fifth endocrine cell type in human pancreatic islets. The abundance of ε-cells in adult pancreas is extremely low, which has hampered the investigation on the molecular pathways regulating the development and the function of this cell type. In this study, we explored the molecular features defining the function of pancreatic ε-cells isolated from adult non-diabetic donors using single-cell RNA sequencing technology. We focus on transcription factors, cell surface receptors...
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