Data from: Zinc supplementation inhibits complement activation in age-related macular degeneration

Dzenita Smailhodzic, Freekje Van Asten, Anna M. Blom, Frida C. Mohlin, Anneke I. Den Hollander, Johannes P. H. Van De Ven, Ramon A. C. Van Huet, Joannes M. M. Groenewoud, Yuan Tian, Tos T. J. M. Berendschot, Yara T. E. Lechanteur, Sascha Fauser, Chris De Bruijn, Mohamed R. Daha, Gert Jan Van Der Wilt, Carel B. Hoyng & B. Jeroen Klevering
Age-related macular degeneration (AMD) is the leading cause of blindness in the Western world. AMD is a multifactorial disorder but complement-mediated inflammation at the level of the retina plays a pivotal role. Oral zinc supplementation can reduce the progression of AMD but the precise mechanism of this protective effect is as yet unclear. We investigated whether zinc supplementation directly affects the degree of complement activation in AMD and whether there is a relation between serum...
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