Comparative transcriptomics of the venoms of continental and insular radiations of West African cones

Samuel Abalde, Manuel J. Tenorio, Carlos M. L. Afonso & Rafael Zardoya
The transcriptomes of the venom glands of 13 closely related species of vermivorous cones endemic to West Africa from genera Africonus and Varioconus were sequenced and venom repertoires compared within a phylogenetic framework. The total number of conotoxin precursors per species varied between 108 and 221. Individuals of the same species shared about one fourth of the total conotoxin precursors. The number of common sequences was drastically reduced in the pairwise comparisons between closely related...
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