Data from: Early antiretroviral therapy and potent second-line drugs could decrease HIV incidence of drug resistance

Mingwang Shen, Yanni Xiao, Libin Rong, Lauren Ancel Meyers, Steve E. Bellan & Steven E. Bellan
Early initiation of antiretroviral therapy (ART) reduces the risk of drug-sensitive HIV transmission but may increase the transmission of drug-resistant HIV. We used a mathematical model to estimate the long-term population-level benefits of ART and determine the scenarios under which earlier ART (treatment at 1 year post-infection, on average) could decrease simultaneously both total and drug-resistant HIV incidence (new infections). We constructed an infection-age-structured mathematical model that tracked the transmission rates over the course of...
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