Data from: Insulin-insensitivity of male genitals maintains reproductive success in Drosophila

Austin P. Dreyer & Alexander W. Shingleton
For most arthropod species, male genital size is relatively implastic in response to variation in developmental nutrition, such that the genitals in large well-fed males are similar in size to those in small poorly-fed males. In Drosophila melanogaster, reduced nutritional plasticity of the male genitalia is a consequence of low insulin sensitivity through a tissue-specific reduction in expression of FOXO, a negative growth regulator. Despite an understanding of the proximate developmental mechanisms regulating organ size,...
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