Data from: Acute, delayed and chronic remote ischemic conditioning is associated with downregulation of mTOR and enhanced autophagy signaling

Sagar Rohailla, Nadia A. Clarizia, Michel Sourour, Wesam Sourour, Nitai Gelber, Can Wei, Jing Li, Andrew N. Redington & Nadia Clarizia
Background - Remote ischemic conditioning (RIC), induced by brief periods of limb ischemia has been shown to decrease acute myocardial injury and chronic responses after acute coronary syndromes. While several signaling pathways have been implicated, our understanding of the cardioprotection and its underlying mediators and mechanisms remains incomplete. In this study we examine the effect of RIC on pro- autophagy signaling as a possible mechanism of benefit. Methods and Results - We examined the role...
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