Data from: Environmental enrichment normalizes hippocampal timing coding in a malformed hippocampus

Amanda E. Hernan, J. Matthew Mahoney, Willie Curry, Greg Richard, Marcella M. Lucas, Andrew Massey, Gregory L. Holmes, Rodney C. Scott & Rod C. Scott
Neurodevelopmental insults leading to malformations of cortical development (MCD) are a common cause of psychiatric disorders, learning impairments and epilepsy. In the methylazoxymethanol (MAM) model of MCDs, animals have impairments in spatial cognition that, remarkably, are improved by post-weaning environmental enrichment (EE). To establish how EE impacts network-level mechanisms of spatial cognition, hippocampal in vivo single unit recordings were performed in freely moving animals in an open arena. We took a generalized linear modeling approach...
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