Data from: Using long-term experimental evolution to uncover the patterns and determinants of molecular evolution of an Escherichia coli natural isolate in the streptomycin treated mouse gut

Mathilde Lescat, Launay Adrien, Mohamed Ghalayini, Mélanie Magnan, Jérémy Glodt, Coralie Pintard, Sara Dion, Erick Denamur, Olivier Tenaillon & Adrien Launay
Though microbial ecology of the gut is now a major focus of interest, little is known about the molecular determinants of microbial adaptation in the gut. Experimental evolution coupled with whole genome sequencing can provide insights of the adaptive process. In vitro experiments have revealed some conserved patterns: intermediate convergence, epistatic interactions between beneficial mutations and mutations in global regulators. To test the relevance of these patterns and to identify the selective pressures acting in...
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