The cell adhesion molecule Sdk1 shapes assembly of a retinal circuit that detects localized edges

Pierre-Luc Rochon, Catherine Theriault, Aline Giselle Rangel Olguin & Arjun Krishnaswamy
Nearly 50 different mouse retinal ganglion cell (RGC) types sample the visual scene for distinct features. RGC feature selectivity arises from its synapses with a specific subset of amacrine (AC) and bipolar cell (BC) types, but how RGC dendrites arborize and collect input from these specific subsets remains poorly understood. Here we examine the hypothesis that RGCs employ molecular recognition systems to meet this challenge. By combining calcium imaging and type-specific histological stains we define...
1 citation reported since publication in 2021.
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