All-trans retinoic acid induces synaptopodin-dependent metaplasticity in mouse dentate granule cells

Maximilian Lenz, Amelie Eichler, Pia Kruse, Julia Muellerleile, Thomas Deller, Peter Jedlicka & Andreas Vlachos
Previously we showed that the vitamin A metabolite all-trans retinoic acid (atRA) induces synaptic plasticity in acute brain slices prepared from the mouse and human neocortex (Lenz et al., 2021). Depending on the brain region studied, distinct effects of atRA on excitatory and inhibitory neurotransmission have been reported. Here, we used intraperitoneal injections of atRA (10 mg/kg) in adult C57BL/6J mice to study the effects of atRA on excitatory and inhibitory neurotransmission in the mouse...
1 citation reported since publication in 2021.
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