Data from: Reducing therapeutic misconception: a randomized intervention trial in hypothetical clinical trials

Paul P. Christopher, Paul S. Appelbaum, Debbie Truong, Karen Albert, Louise Maranda, Charles Lidz & Charles Lidz
Background: Participants in clinical trials frequently fail to appreciate key differences between research and clinical care. This phenomenon, known as therapeutic misconception, undermines informed consent to clinical research, but to date there have been no effective interventions to reduce it and concerns have been expressed that to do so might impede recruitment. We determined whether a scientific reframing intervention reduces therapeutic misconception without significantly reducing willingness to participate in hypothetical clinical trials. Methods: This prospective...
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