Data from: Prolonged fasting-induced metabolic signatures in human skeletal muscle of lean and obese men

Ann Mosegaard Bak, Mikkel Holm Vendelbo, Britt Christensen, Rikke Viggers, Bo Martin Bibby, Jørgen Rungby, Jens Otto Jørgensen, Niels Møller, Niels Jessen & Jens Otto Lunde Jørgensen
Insulin resistance is a well-known physiological adaptation to prolonged fasting in healthy skeletal muscle. Obesity is associated with insulin resistance and metabolic inflexibility in skeletal muscle, and a pronounced increase in the risk of metabolic complications. Under the hypothesis that the metabolic traits of insulin resistance associated with prolonged fasting are different from insulin resistance associated with obesity, we examined nine obese and nine lean participants during 12 and 72h of fasting, respectively. Insulin resistance...
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