Data from: A point mutation in a herpesvirus co-determines neuropathogenicity and viral shedding

Mathias Franz, Laura B. Goodman, Gerlinde R. Van De Walle, Nikolaus Osterrieder, Alex D. Greenwood, Laura Goodman, Gerlinde Van De Walle & Alex Greenwood
A point mutation in the DNA polymerase gene in equine herpesvirus type 1 (EHV-1) is one determinant for the development of neurological disease in horses. Three recently conducted infection experiments using domestic horses and ponies failed to detect statistically significant differences in viral shedding between the neuropathogenic and non-neuropathogenic variants. These results were interpreted as suggesting the absence of a consistent selective advantage of the neuropathogenic variant and therefore appeared to be inconsistent with a...
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