Modelling the impact of antibody-dependent enhancement on disease severity of ZIKV and DENV sequential and co-infection

Biao Tang, Yanni Xiao, Beate Sander, Manisha A. Kulkarni & Jianhong Wu
Human infections with viruses of the genus Flavivirus, including dengue virus (DENV) and Zika virus (ZIKV), are of increasing global importance. Due to antibody dependent enhancement, secondary infection with one Flavivirus following primary infection with another {\it Flavivirus} can result in a significantly larger peak viral load with a much higher risk of severe disease. Although several mathematical models have been developed to quantify the virus dynamics in the primary and secondary infections of DENV,...
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These counts follow the COUNTER Code of Practice, meaning that Internet robots and repeats within a certain time frame are excluded.
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