Gut microbiota in non-obese adolescent girls with polycystic ovary syndrome: effects of randomized treatments

Lourdes Ibáñez, Cristina Garcia-Beltran, Rita Malpique, Belen Carbonetto, Pedro González-Torres, Desirée Henares, Pedro Brotons, Carmen Muñoz-Almagro, Abel López-Bermejo & Francis De Zegher
Context: Women and obese adolescent girls with polycystic ovary syndrome (PCOS) have altered gut microbiota. Objective: To study the gut microbiota composition of non-obese adolescent girls with PCOS and the effects of randomized pharmacological treatments. Design: Randomized, open-label, single-center controlled trial. Settings: Endocrinology Department, University Hospital. Participants: 30 girls with PCOS [age 15.8 years; body mass index (BMI) 25 kg/ m2] and 31 controls [age 15.9 years; BMI 22 kg/ m2]. Intervention: PCOS girls were...
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